Your Sedentary Lifestyle Is Turning You Into a Nervous Wreck

The link between a sedentary lifestyle and anxiety was reinforced recently by new research comparing sedentary mice and mice that exercise. The study, published in the Journal of Neuroscience and covered in the New York Times, where I first learned about it, suggests that habitual inactivity can cause increased anxiety in animals that don’t move around much.

Researchers at Princeton University compared the behavior and brains of mice that were allowed to exercise on wheels in their cages to those who instead "sat quietly." The mice that were active showed more inclination to explore new environments when given the chance, an indication of less anxiety. When dunked in cold water, as stressful for mice as it is for humans, the running mice reacted more calmly than the sedentary ones.